The cees dekker Diaries
The cees dekker Diaries
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‘The next is nanopores, that's our oldest line of investigation and that has now resulted in DNA sequencers determined by nanopores. We pull particular person DNA strands by way of a nanopore and may then go through off the nucleotide sequence. Extremely just lately, we even managed to go through out just one protein for the first time using This system. But this line of investigate is not simply about producing equipment, but additionally about real Organic inquiries.
It had been only in the nineties nevertheless, when nanotechnology had Highly developed to some amount exactly where solitary molecules could be manipulated, that the primary experimental equipment started to seem.
[Laughs] ‘It was definitely a great risk! At some time, I had been very well informed that it could go Mistaken and that I could turn out to be much less thriving, but I just disregarded that. Curiosity has generally been my strongest driving power. And fortuitously it all labored out.’
Considering that 2000, Dekker has shifted the main target of his get the job done towards biophysics in which he experiments the properties of solitary biomolecules and cells utilizing the applications of nanotechnology. This transformation of subject was pushed by his fascination for the exceptional operating of Organic molecular buildings, and by the extended-phrase point of view a large number of attention-grabbing discoveries can be expected On this discipline.[5] Recent traces of investigate in his biophysics team are in the areas of:[six]
That could be a desire of mine and we set to work that has a scrumptious dose of naivety. This is certainly something that will probably produce amazing results in the more time time period, but that does not issue. You shouldn't only want to work within the issues of tomorrow, but also within the issues of the day right after tomorrow.’
Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en satisfied 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak https://www.ceesdekker.net van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
Duration Charge of specific carbon nanotubes by nanostructuring Together with the scanning tunneling microscope
2000, discovery that nanotubes can have extraordinary huge latest densities; resolved the controversial situation of Digital transport by DNA molecules by measurements of insulating actions at the single molecule stage; and demonstration of the AFM technique for solitary-molecule manipulation of nanotubes
Comprehension elementary procedures regulating the spatial and dynamic organisation with the DNA in Stay cells.
‘The fantastically delicate way during which components in nature functionality under no circumstances ceases to amaze me. If we clear up the puzzle of how existence came into being, I hope that my amazement for the complexity of development may have amplified and with it my awe for that greatness on the Creator.’
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Cees Dekker is Distinguished University Professor at TU Delft. Skilled like a physicist, he pioneered nanotechnology with several discoveries on carbon nanotubes inside the nineties. Given that 2000, he moved to single-molecule biophysics and nanobiology. His present study focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, especially SMC motor protein; and (iii) developing a residing synthetic mobile from lifeless molecules. Dekker can be an elected member of the KNAW and fellow into the APS as well as IOP.
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It had been an exceedingly fascinating time, for the duration of which I received plenty of guidance from Delft College of Technologies, the place I had been a professor at some time, and I began many collaborations with molecular biologists. That helped me find out a good deal.’